Best Places to Live in Southern Indiana (2025 Guide)
Southern Indiana has a personality all its own. It’s where the rolling hills meet the Ohio River, where historic towns blend with modern amenities, and where life moves just a little slower.
Whether you're looking for scenic drives, great schools, riverside living, or a tight-knit community, this corner of the state delivers. Let’s explore the best places to call home in Southern Indiana in 2025.
Planning a move? Don’t miss our guides to the Best Places to Live in Northern Indiana, Best Suburbs to Buy a Home in Indiana, and Best Towns in Indiana for First-Time Home Buyers.
New Albany, IN: Ideal for First-Time Home Buyers and Commuters
Just across the Ohio River from Louisville, New Albany offers small-town affordability with big-city access. Its downtown is thriving with breweries, boutiques, and historic buildings, and housing prices are still accessible.
Why live in New Albany?
Walkable neighborhoods with historic homes
Vibrant river views, festivals, and a growing foodie culture
An easy commute into Louisville, KY
Ideal for: First-time buyers and commuters.

Jeffersonville, IN: Best for Families and Young Professionals
Also near Louisville, Jeffersonville is booming. With new developments, strong schools, and riverfront fun like concerts and the Big Four Bridge, it’s one of the fastest-growing areas in Southern Indiana.
Why live in Jeffersonville?
New subdivisions paired with a revitalized downtown
Strong schools and family amenities
A perfect mix of historic charm and modern growth
Ideal for: Young professionals, families, and remote workers.
Columbus, IN: An Architectural Gem for Design Lovers
Known for its world-class architecture, Columbus combines creative flair with family-friendly living. It's safe, walkable, and full of unique cultural attractions for a mid-sized town.
Why live in Columbus?
Modernist homes and historic districts
Safe neighborhoods with excellent schools
A unique blend of industry, design, and community
Ideal for: Design lovers and families seeking affordability.

Jasper, IN: A Safe, Community-Focused Town for Retirees
Ranked among the best small towns in Indiana, Jasper offers strong civic pride, low crime, and excellent public services. The town square stays active year-round with festivals and events.
Why live in Jasper?
Affordable cost of living and quality schools
A strong sense of community and cleanliness
Trails, parks, and plenty of outdoor recreation
Ideal for: Families and retirees.
Dive deeper into life here with our Small Town Breakdown: Jasper, Indiana for insider details on this southern Indiana standout.

Madison, IN: The Most Scenic Town on the Ohio River
With one of the largest historic districts in the U.S., Madison feels like a time capsule. Its cobblestone streets, art galleries, and vibrant riverfront make it a scenic, historic haven.
Why live in Madison?
Ohio River views and historic homes
A thriving arts community and downtown shops
A slower, more scenic lifestyle
Ideal for: Retirees, remote workers, and history buffs.
Tell City, IN: Most Affordable Town for Outdoor Enthusiasts
Nestled near the Hoosier National Forest, Tell City offers affordability, space, and outdoor access. It’s a peaceful place for those who want nature and community.
Why live in Tell City?
Affordable homes with rural charm
Easy access to hiking, boating, and camping
A friendly, laid-back pace of life
Ideal for: Budget-conscious buyers and outdoor enthusiasts.
Want to go deeper? Check out our Small Town Breakdown: Tell City, Indiana for a closer look at this southern gem.
Your Top Questions About Southern Indiana Living
What is the best place to live near Louisville, KY?
New Albany and Jeffersonville are top choices for their quick commutes, revitalized downtowns, and strong schools.
What is the most scenic town in Southern Indiana?
Madison is widely considered the most scenic due to its historic architecture, Ohio River views, and vibrant arts scene.
What’s the best family-friendly town in Southern Indiana?
Jasper ranks highly for safety, excellent schools, and strong community pride.
What's the cost of living like in Southern Indiana?
The cost of living is generally lower than the national average, especially in towns like Jasper and Tell City, making it an attractive option for budget-conscious individuals and families.Thinking About Moving South?
Thinking About Moving South?
From Bloomington’s college-town buzz to Tell City’s quiet country life, Southern Indiana offers a wide range of lifestyles. Whether you want to be near water, woods, or a walkable downtown, there’s a home waiting for you.
Planning a move? Don’t miss our guides to the Best Places to Live in Northern Indiana, Best Suburbs to Buy a Home in Indiana, and Best Towns in Indiana for First-Time Home Buyers.